Postdoc. Alumni김도연 / Doyoun Kim / Ph.D. / 2013-11 ~ 2018-10 

37. Kim H*, Kim D*, Cho Y, Kim K, Roh JD, Kim Y, Yang E, Kim SS, Ahn S, Kim H, Kang H, Bae Y**, and Kim E** . (2022).
Early postnatal serotonin modulation prevents adult-stage deficits in Arid1b-deficient mice through synaptic transcriptional reprogramming.
Nat Commun 13:5051. (abstract)

36. Bae M*, Roh JD*, Kim Y, Kim SS, Han HM, Yang E, Kang H, Lee S. Kim JY, Kang R, Jung H, Yoo T, Kim H, Kim D, Oh H, Han S, Kim D, Han, J, Bae YC, Kim H, Ahn S, Chan AM, Lee D, Kim J, and Kim E. (2021). SLC6A20 transporter: a novel regulator of brain glycine homeostasis and NMDAR function.
EMBO Mol Med e12632. (abstract)

35. Jang S, Yang E, Kim D, Kim H, and Kim E. (2020).Clmp regulates AMPA and kainate receptor responses in the neonatal hippocampal CA3 and kainate seizure susceptibility in mice.
Front Synaptic Neurosci 12:567075. (abstract)

34. Shin W*, Kim K*, Serraz B, Cho YS, Kim D, Kang M, Lee EJ, Lee H, Bae YC, Paoletti P, and Kim E. (2020).
Early correction of synaptic long-term depression improves abnormal anxiety-like behavior in adult GluN2B-C456Y-mutant mice.
PLoS Biol 18:e3000717. (abstract)

33. Kim K*, Shin W*, Kang M, Lee S, Kim D, Kang R, Jung Y, Cho Y, Yang E, Kim H, Bae YC, and Kim E. (2020).
Presynaptic PTPs regulates postsynaptic NMDA receptor function through direct adhesion-independent mechanisms.
eLife 9:e54224. (abstract)

32. Yook C, Kim K, Kim D, Kang H, Kim SG, Kim E#, and Kim SY#. (2019).
A TBR1-K228E mutation induces Tbr1 upregulation, altered cortical distribution of interneurons, increased inhibitory synaptic transmission, and autistic-like behavioral deficits in mice.
Front Mol Neurosci 12:241. (abstract)

31. Yoo YE, Yoo T, Lee S, Lee J, Kim D, Han HM, Bae YC, Kim E. (2019).
Shank3 mice carrying the human Q321R mutation display enhanced self-grooming, abnormal electroencephalogram patterns, and suppressed neuronal excitability and seizure susceptibility.
Front Mol Neurosci 12:155. (abstract)

30. Shin W*, Kweon H*, Kang R*, Kim D, Kim K, Kang M, Kim SY, Hwang SN, Kim JY, Yang E, Kim H, and Kim E. (2019).
Scn2a haploinsufficiency in mice suppresses hippocampal neuronal excitability, excitatory synaptic drive, and long-term potentiation, and spatial learning and memory.
Front Mol Neurosci 12:145. (abstract)

29. Kim D, Hur J, Han JH, Ha SC, Shin D, Lee S, Park S, Sugiyama H, and Kim KK. (2018).
Sequence preference and structural heterogeneity of BZ junctions.
Nucleic Acids Research, in press.

28. Chung C*, Ha S*, Kang H, Lee J, Um SM, Yan H, Yoo YE, Yoo T, Jung H, Lee D, Lee E, Lee S, Kim J, Kim R, Kwon Y, Kim W, Kim H, Duffney L, Kim D, Mah W, Won H, Mo S, Kim JY, Lim CS, Kaang BK, Boeckers TM, Chung Y, Kim H, Jiang YH, and Kim E. (2019).
Early correction of NMDAR function improves autistic-like behaviors in adult Shank2–/– mice.
Biol Psychiatry 85:534-543. (abstract)

27. Li Y*, Kim R*, Cho YS, Song WS, Kim D, Kim K, Roh JD, Chung C, Park H, Yang E, Kim SJ, Ko J, Kim H, Kim MH, Bae YC, and Kim E. (2018).
Lrfn2-mutant mice display suppressed synaptic plasticity and inhibitory synapse development and abnormal social communication and startle response.
J Neurosci 38:5872-5887. (abstract)

26. Won SY*, Kim CY*, Kim D, Ko J, Um JW, Lee SB, Buck M, Kim E, Heo WD, Lee JO, and Kim HM. (2017). LAR-RPTP Clustering Is Modulated by Competitive Binding Between Synaptic Adhesion Partners and Heparan Sulfate. 

Front Mol Neurosci 10:327. (abstract)

25. Cheon CK, Lim SH, Kim YM, Kim D, Lee NY, Yoo TS, Kim NS, Kim E, and Lee JR. (2017).
Autosomal dominant transmission of complicated hereditary spastic paraplegia due to a dominant negative mutation of KIF1A, SPG30 gene.
Sci Rep 7:12527. (abstract)

24. Kim JA*, Kim D*, Won SY, Han KA, Park D, Cho E, Yun N, An HJ, Um JW, Kim E, Lee JO, Ko J, and Kim HM. (2017).
Structural Insights into Modulation of Neurexin-Neuroligin Trans-synaptic Adhesion by MDGA1/Neuroligin-2 Complex
Neuron 94:1121-1131. (abstract)

23. Lee Y*, Kim D*, Ryu JR, Zhang Y, Kim S, Kim Y, Lee B Sun W, Han K. (2017).
Phosphorylation of CYFIP2, a component of WAVE regulatory complex, regulates dendritic spine density and neurite outgrowth in cultured hippocampal neurons potentially by affecting the complex assembly.
NeuroReport  28(12):749-754. (abstract)

22. Kim H, Chaurasia KA, Kim T, Choi J, Ha SC, Kim D, Kim KK. (2017).
Structural and functional study of ChuY from Escherichia coli strain CFT073.
Biochemical and Biophysical Research Communications 482(4):1176-1182. (abstract)


21. Lie E, Ko JS, Choi SY, Roh JD, Cho YS, Noh R, Kim D, Li Y, Kang H, Cho TY, Nam J, Mah W, Lee D, Lee SG, Kim HM, Kim H, Choi SY, Um JW, Kang MG, Bae YC, Ko J, and Kim E. (2016).
SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3–LAR adhesion.
Nat Commun 7:12328. (abstract)

20. Subramani VK, Kim D, Yun K, Kim KK. (2016).
Structural and functional studies of a large winged Z-DNA binding domain of Danio rerio protein kinase PKZ
FEBS lett, in press.  (abstract)


19. Choi Y*, Nam J*, Whitcomb DJ*, Song YS*, Kim D, Jeon S, Um JW, Lee SG, Woo J, Kwon S, Li Y, Mah W, Kim HM, Ko J, Cho K, and Kim E. (2016).
SALM5 trans-synaptically interacts with LAR-RPTPs in a splicing-dependent manner to regulate synapse development.
Sci Rep 6:26676. (abstract)


18. Moh SH, Kulkarni A, San BH, Lee JH, Kim D, Park K, Lee MH, Kim T, Kim KK. (2016)
Photocurrent enhancement of SiNW-FETs by integrating protein-shelled CdSe quantum dots
Nanoscale 28;8(4):1921-5. (abstract)


17. Jang S*, Oh D*, Lee Y*, Hosy E*, Shin H, van Riesen C, Whitcomb D, Warburton JM, Jo J, Kim D, Kim SG, Um SM, Kwon SK, Kim MH, Roh JD, Woo J, Jun H, Lee D, Mah W, Kim H, Kaang BK, Cho K, Rhee JS, Choquet D, and Kim E. (2016).
Synaptic adhesion molecule IgSF11 regulates synaptic transmission and plasticity.
Nat Neurosci 19:84-93. (abstract)


16. Kim H, Choi J, Kim D and Kim KK. (2015).
Crystal structure analysis of c4763, a uropathogenic Escherichia coli specific protein.
Acta Crystallogr F Struct Biol Commun 71(Pt 8):1042-1047.  (abstract)


15. Ylikallio E, Kim D, Isohanni P, Auranen M, Lönnqvist T, Kim E, and Tyynismaa H. (2015).
Dominant transmission of de novo KIF1A motor domain variant underlying pure spastic paraplegia.
Eur J Hum Genet 23(10):1427-1430. (abstract)


14. Lee JR, Srour M, Kim D, Hamdan FF, Lim SH, Brunel-Guitton C, Décarie JC, Rossignol E, Mitchell GA, Schreiber A, Moran R, Van Haren K, Richardson R, Nicolai J, Oberndorff KM, Wagner JD, Boycott KM, Rahikkala E, Junna N, Tyynismaa H, Cuppen I, Verbeek NE, Stumpel CT, Willemsen MA, de Munnik SA, Rouleau GA, Kim E, Kamsteeg EJ, Kleefstra T, Michaud JL. (2015).
De novo mutations in the motor domain of KIF1A cause cognitive impairment, spastic paraparesis, axonal neuropathy and cerebellar atrophy.
Hum Mutat 36:69-78. (abstract)

13. Um JW, Kim KH, Park BS, Choi Y, Kim D, Kim CY, Kim SJ, Kim M, Ko JS, Lee SG, Choii G, Nam J, Heo WD, Kim E, Lee JO, Ko J, and Kim HM. (2014)
Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion.
Nat Commun 5:5423. (abstract)


12. Nguyen D, Pandian R, Kim D, Ha SC, Yoon HJ, Kim KS, Yun KH, Kim JH, Kim KK (2014).
Structural and kinetic bases fo the metal preference of the M18 aminopeptidase from Pseudomonas aeruginosa
Biochemical and Biophysical Research Communications 447(1):101-107. (abstract)


11. Jun HJ, Nguyen AH, Kim YH, Park KH, Kim D, Kim KK, Sim SJ (2014).
Distinct Rayleigh Scattering from Hot Spot Mutant p53 Proteins Reveals Cancer Cells.
small 10(14):2954-2962. (abstract)


10. Kim D, Hur J, Park K, Bae S, Shin D, Ha SC, Hwang HY, Honhng S, Lee JH, Lee S, Kim YG, Kim KK (2014).
Distinct Z-DNA binding mode of a PKR-like protein kinase containing a Z-DNA binding domain (PKZ)
Nucleic Acids Research 42(9):5937-5948. (abstract)


9. Bae S, Kim Y, Kim D, Kim KK, Kim YG, Honhg S. (2013).
Energetics of Z-DNA Binding Protein-Mediated Helicity Reversals in DNA, RNA, and DNA-RNA Duplexes.
The Journal of Physical Chemistry B 117:(44):13866-13871. (abstract)


8. Kim D, Kim KK (2013).
Glutamyl aminopeptidase (Lactococcus)
Handbook of Proteolytic Enzymes 3rd Edition, chapter 369:1631 (abstract)


7. Bae S, Kim D, Kim KK, Kim YG, Honhg S. (2011).
Instrinsic Z-DNA is stabilized by the conformational selection mechanism of Z-DNA-binding proteins
Journal of American Chemical Society 133(4):668. (abstract) 

6. Kim D, Lee YH, Hwang HY, Kim KK, Park HJ. (2010).
Z-DNA binding proteins as targets for structure-based virtual screening
Current Drug Targets 11(3):335. (abstract)


5. Kim D, San BH, Moh SH, Park HJ, Kim DY, Lee SH, Kim KK. (2009).
Structural basis for the substrate specificity of pepA from Streptococcus pneumoniae, a dodecameric tetrahedral protease
Biochemical and Biophysical Research Communications 391(1):431. (abstract)


4. Kim D, Reddy S, Kim DY, Rich A, Lee SH, Kim KK, Kim YG. (2009).
Base extrusion is found at helical jnctions between right- and left-handed forms of DNA and RNA
Nucleic Acids Research 37(13):4353. (abstract)


3. Kim D, Hwang HY, Kim YG, Kim KK. (2009).
Crystallization and preliminary X-ray crystallographic studies of the Z-DNA-binding domain of a PKR-like kinase (PKZ) in complex with Z-DNA
Acta crystallographica section F Structural Biology and Crystallization Communications 65(3):267. (abstract)

2. Ha SC, Kim D, Hwang HY, Rich A, Kim YG, Kim KK. (2009).
The Crystal structure of the second Z-DNA binding domain of human DAI (ZBP1) in complex with Z-DNA reveals an unusual binding mode to Z-DNA.
Proceedings of the National Academy of Sciences 105(52):2067. (abstract)


1. Quyen DV, Ha SC, Kim D, Lee SH, Park SJ, Kim KK, Kim YG. (2007).
Binding Surface in Zβ Domain from Human ZBP1 Does Not Require Conserved Proline Residues for Z-DNA Binding and B-to-Z-DNA Conversion Activities
Bulletin of the Korean Chemical Society 28(12):2539. (abstract)